The auditory midbrain of people with tinnitus: Abnormal sound-evoked activity revisited
نویسندگان
چکیده
منابع مشابه
Long-Lasting Sound-Evoked Afterdischarge in the Auditory Midbrain
Different forms of plasticity are known to play a critical role in the processing of information about sound. Here, we report a novel neural plastic response in the inferior colliculus, an auditory center in the midbrain of the auditory pathway. A vigorous, long-lasting sound-evoked afterdischarge (LSA) is seen in a subpopulation of both glutamatergic and GABAergic neurons in the central nucleu...
متن کاملStatistical mapping of sound-evoked activity in the mouse auditory midbrain using Mn-enhanced MRI
Manganese-enhanced MRI (MEMRI) has been developed to image brain activity in small animals, including normal and genetically modified mice. Here, we report the use of a MEMRI-based statistical parametric mapping method to analyze sound-evoked activity in the mouse auditory midbrain, the inferior colliculus (IC). Acoustic stimuli with defined frequency and amplitude components were shown to acti...
متن کاملAsymmetric temporal interactions of sound-evoked excitatory and inhibitory inputs in the mouse auditory midbrain.
In the auditory midbrain, synaptic mechanisms responsible for the precise temporal coding of inputs in the brainstem are absent. Instead, in the inferior colliculus (IC), the diverse temporal firing patterns must be coded by other synaptic mechanisms, about which little is known. Here, we demonstrate the temporal characteristics of sound-evoked excitatory and inhibitory postsynaptic currents (s...
متن کاملAuditory evoked magnetic fields in individuals with tinnitus☆
Some forms of tinnitus are likely to be perceptual consequences of altered neural activity in the central auditory system triggered by damage to the auditory periphery. Animal studies report changes in the evoked responses after noise exposure or ototoxic drugs in inferior colliculus and auditory cortex. However, human electrophysiological evidence is rather equivocal: increased, reduced or no ...
متن کاملLate Auditory evoked potentials in individuals with tinnitus.
UNLABELLED Long latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level. AIM To characterize the LLAEP in individuals with and without tinnitus exposed to occupational noise. METHOD Cross-sectional contemporary cohort, prospective study. Sixty subjects exposed to occupational noise...
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ژورنال
عنوان ژورنال: Hearing Research
سال: 2009
ISSN: 0378-5955
DOI: 10.1016/j.heares.2009.08.005